Toward the Identification of Natural Antiviral Drug Candidates against Merkel Cell Polyomavirus: Computational Drug Design Approaches

Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens and play an important role in the growth-promoting activities of oncoproteins. Truncated LT promotes tumorigenicity as well as h...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Amer H. Asseri, Md. Jahidul Alam, Faisal Alzahrani, Ahmed Khames, Mohammad Turhan Pathan, Mohammed A. S. Abourehab, Salman Hosawi, Rubaiat Ahmed, Sifat Ara Sultana, Nazia Fairooz Alam, Nafee-Ul Alam, Rahat Alam, Abdus Samad, Sushil Pokhrel, Jin Kyu Kim, Foysal Ahammad, Bonglee Kim, Shing Cheng Tan
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-04-01
Serie:	Pharmaceuticals
Soggetti:	Merkel cell polyomavirus Merkel cell carcinomas drug design molecular docking ADMET MD simulation
Accesso online:	https://www.mdpi.com/1424-8247/15/5/501
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!