Structural effects of inosine substitution in telomeric DNA quadruplex
The telomeric DNA, a distal region of eukaryotic chromosome containing guanine-rich repetitive sequence of (TTAGGG)n, has been shown to adopt higher-order structures, specifically G-quadruplexes (G4s). Previous studies have demonstrated the implication of G4 in tumor inhibition through chromosome ma...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2024-01-01
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| coleção: | Frontiers in Chemistry |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fchem.2024.1330378/full |
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