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Combinational treatments of RNA interference and extracellular vesicles in the spinocerebellar ataxia

Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disease (ND) with a high mortality rate. Symptomatic treatment is the only clinically adopted treatment. However, it has poor effect and serious complications. Traditional diagnostic methods [such as magnetic resonance imaging (...

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Principais autores: Yingying Ding, Yong Zhang, Xuehong Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-10-01
coleção:Frontiers in Molecular Neuroscience
Assuntos:
extracellular vesicle
RNA interference
miRNA
siRNA
shRNA
spinocerebellar ataxia
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1043947/full
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