Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis

Background: Fucoidan (FPS) has been widely used to treat renal fibrosis (RF) in patients with diabetic kidney disease (DKD); however, the precise therapeutic mechanisms remain unclear. Recently, research focusing on inflammation-derived podocyte pyroptosis in DKD has attracted increasing attention....

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Autors principals:	Mei-Zi Wang, Jie Wang, Dong-Wei Cao, Yue Tu, Bu-Hui Liu, Can-Can Yuan, Huan Li, Qi-Jun Fang, Jia-Xin Chen, Yan Fu, Bing-Ying Wan, Zi-Yue Wan, Yi-Gang Wan, Guo-Wen Wu
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-03-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	fucoidan diabetic kidney disease renal fibrosis podocyte pyroptosis NLRP3 inflammasome
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2022.790937/full
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