<i>TYMS</i> 3′-UTR Polymorphism: A Novel Association with FOLFIRINOX-Induced Neurotoxicity in Pancreatic Cancer Patients

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal malignancy that has the worst 5-year survival rate of all of the common malignant tumors. Surgery, chemotherapy, and/or chemoradiation remain the main tactics for PDAC treatment. The efficacy of chemotherapy is often compromised because of th...

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Autori principali:	Marina Emelyanova, Ilya Pokataev, Igor Shashkov, Elena Kopantseva, Vladimir Lyadov, Rustam Heydarov, Vladimir Mikhailovich
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-12-01
Serie:	Pharmaceutics
Soggetti:	<i>TYMS</i> <i>GSTP1</i> rs11280056 pancreatic ductal adenocarcinoma drug-induced toxicity FOLFIRINOX
Accesso online:	https://www.mdpi.com/1999-4923/14/1/77
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