Safety and Efficacy of Combined Injection of Pure-μ-Opioid Agonist with Tramadol as an Opioid Induction Agent for Opioid-Naïve Cancer Patients

Background: Tramadol is known to provide synergistic analgesia when used in combination with morphine. Objectives: The aims of this study were: (1) to introduce an opioid combination therapy using pure-μ-opioid receptor agonist (OPI) + tramadol injections (OPI + tramadol) and (2) to elucidate safety...

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Auteurs principaux:	Tetsumi Sato, Shigeki Ono, Tetsu Sato, Rei Tanaka, Yoshiko Kamo, Tomomi Suzuki
Format:	Artigo
Langue:	Inglês
Publié:	SAGE Publishing 2024-10-01
Collection:	Palliative Medicine Reports
Sujets:	cancer pain μ-opioid receptor agonist opioid combination therapy opioid naïve tramadol
Accès en ligne:	https://www.liebertpub.com/doi/10.1089/pmr.2023.0061
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