Evaluation of Bayesian Linear Regression models for gene set prioritization in complex diseases.
Genome-wide association studies (GWAS) provide valuable insights into the genetic architecture of complex traits, yet interpreting their results remains challenging due to the polygenic nature of most traits. Gene set analysis offers a solution by aggregating genetic variants into biologically relev...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2024-11-01
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| Serier: | PLoS Genetics |
| Online adgang: | https://doi.org/10.1371/journal.pgen.1011463 |
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