Chimeric Antigen Receptor T Cell Immunotherapy for Autoimmune Rheumatic Disorders: Where Are We Now?

Chimeric antigen receptor (CAR) T cell immunotherapy has changed the landscape of B cell hematological malignancies’ management, while it has recently shown promising results in the treatment of refractory autoimmune rheumatic disorders (ARDs). Targeting B cell antigens such as CD19 and BCMA, CAR-T...

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Main Authors: Panagiota Anyfanti, Paschalis Evangelidis, Nikolaos Kotsiou, Anna Papakonstantinou, Ioannis Eftychidis, Ioanna Sakellari, Theodoros Dimitroulas, Eleni Gavriilaki
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-08-01
Serier:Cells
Fag:
autoimmune rheumatic disorders
BCMA
CAR-T cell therapy
CD19
immunotherapy
systemic lupus erythematosus
Online adgang:https://www.mdpi.com/2073-4409/14/16/1242
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