Plasma biomarkers of Alzheimer’s disease and their association with disproportionately enlarged subarachnoid space hydrocephalus

Abstract Background Individuals with both Alzheimer’s Disease (AD) and cerebrospinal fluid (CSF) dynamics disorders, such as idiopathic normal-pressure hydrocephalus (iNPH), exhibit reduced CSF Aβ42 levels, complicating the interpretation of AD biomarkers. However, the influence of CSF dynamics on b...

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Detalhes bibliográficos

Principais autores:	Camilo Bermudez, Ekaterina Hofrenning, Angela J. Fought, Jeffrey L. Gunter, Petrice M. Cogswell, David T. Jones, Christopher G. Schwarz, Val Lowe, Benjamin D. Elder, Ronald C. Petersen, Prashanthi Vemuri, Alicia Algeciras-Schimnich, Michelle M. Mielke, David S. Knopman, Neill R. Graff-Radford, Clifford R. Jack, Jonathan Graff-Radford
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-03-01
coleção:	Fluids and Barriers of the CNS
Assuntos:	Plasma biomarkers CSF dynamics DESH Alzheimer’s disease
Acesso em linha:	https://doi.org/10.1186/s12987-026-00789-3
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