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Exposure of Early Postnatal Oocytes to Chemotherapy Alters the Potential Ovarian Reserve, According to an Ex Vivo Mouse Model

Current safety data on chemotherapy during pregnancy are based on studies which focus on the mother and do not explore reproductive health and fecundity potential within the exposed offspring. We designed this randomized ex vivo animal study to evaluate the effect of chemotherapy on the developing o...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Meghan C. H. Ozcan, Julienne Chaqour, Morgan F. Woodman-Sousa, Kathryn J. Grive
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-12-01
Schriftenreihe:Reproductive Medicine
Schlagworte:
ovarian reserve
oocytes
pregnancy
fetal
chemotherapy
cancer
Online-Zugang:https://www.mdpi.com/2673-3897/4/4/23
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