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Alternative splicing of transposable elements in human breast cancer

Abstract Transposable elements (TEs) drive genome evolution and can affect gene expression through diverse mechanisms. In breast cancer, disrupted regulation of TE sequences may facilitate tumor-specific transcriptomic alterations. We examine 142,514 full-length isoforms derived from long-read RNA s...

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Hoofdauteurs: Alex Nesta, Diogo F. T. Veiga, Jacques Banchereau, Olga Anczukow, Christine R. Beck
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2025-02-01
Reeks:Mobile DNA
Onderwerpen:
Transposable elements
Alternative splicing
Breast cancer
Long-read sequencing
RNA editing
Cancer transcriptomics
Online toegang:https://doi.org/10.1186/s13100-025-00341-4
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