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Can neoadjuvant chemoradiotherapy be omitted in cT2N+ and cT3 mid-rectal cancer: Protocol for a prospective, observational, cohort study (CANO).

<h4>Background</h4>Neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision (TME) is the standard treatment for locally advanced rectal cancer. However, nCRT is associated with significant morbidity, impacting patients' quality of life. Recent advancements in MRI-based risk stratif...

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Principais autores: Feza Karakayali, Cigdem Arslan, Tayfun Bisgin, Ilknur Erenler Bayraktar, Onur Bayraktar, Aras Emre Canda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2025-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0321819
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