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An integrated metaproteomics workflow for studying host-microbe dynamics in bronchoalveolar lavage samples applied to cystic fibrosis disease

ABSTRACT Airway microbiota are known to contribute to lung diseases, such as cystic fibrosis (CF), but their contributions to pathogenesis are still unclear. To improve our understanding of host-microbe interactions, we have developed an integrated analytical and bioinformatic mass spectrometry (MS)...

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Sábháilte in:
Príomhchruthaitheoirí: Monica E. Kruk, Subina Mehta, Kevin Murray, LeeAnn Higgins, Katherine Do, James E. Johnson, Reid Wagner, Chris H. Wendt, John B. O’Connor, J. Kirk Harris, Theresa A. Laguna, Pratik D. Jagtap, Timothy J. Griffin
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology 2024-07-01
Sraith:mSystems
Ábhair:
microbiome
cystic fibrosis
host-pathogen interactions
metaproteomics
metagenomics
bioinformatics
Rochtain ar líne:https://journals.asm.org/doi/10.1128/msystems.00929-23
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