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The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness

The mitochondrial disulphide relay is the key machinery for import and oxidative protein folding in the mitochondrial intermembrane space. Among IMS proteins with unknown function, we identified FAM136A as a new substrate of the mitochondrial disulphide relay. We demonstrate a transient interaction...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Christine Zarges, Hanna Fieler, Robin Alexander Rothemann, Simon Poepsel, Lucas T. Jae, Jan Riemer
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2025-11-01
Cyfres:Redox Biology
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213231725003970
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