High-dose pharmaceutical-grade biotin in patients with demyelinating neuropathies: a phase 2b open label, uncontrolled, pilot study

Abstract Background We proposed to investigate high-dose pharmaceutical-grade biotin in a population of demyelinating neuropathies of different aetiologies, as a proof-of-concept. Methods Phase IIb open label, uncontrolled, single center, pilot study in 15 patients (three groups of five patients) wi...

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Detalhes bibliográficos

Principais autores:	Alain Créange, Emilie Hutin, Frédéric Sedel, Ludivine Le Vigouroux, Jean-Pascal Lefaucheur
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-10-01
coleção:	BMC Neurology
Assuntos:	Biotin Peripheral neuropathies Demyelination Nerve excitability Inflammatory neuropathy CMT neuropathy
Acesso em linha:	https://doi.org/10.1186/s12883-023-03440-y
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