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Uncoupling GP1 and GP2 expression in the Lassa virus glycoprotein complex: implications for GP1 ectodomain shedding

<p>Abstract</p> <p>Background</p> <p>Sera from convalescent Lassa fever patients often contains antibodies to Lassa virus (LASV) glycoprotein 1 (GP1), and glycoprotein 2 (GP2); Immunization of non-human primates with viral vectors expressing the arenaviral glycoprotein complex (GPC) confers full pro...

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Bibliographic Details
Main Authors: Illick Kerry A, Fair Joseph N, Branco Luis M, Illick Megan M, Matschiner Alex, Schoepp Randal, Garry Robert F, Guttieri Mary C
Format: Artigo
Language:Inglês
Published: BMC 2008-12-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/5/1/161
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