Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent

Abstract Background A healthy gastric mucosal epithelium exhibits tumor-suppressive properties. Gastric epithelial cell dysfunction contributes to gastric cancer development. Oxysterols provided from food or cholesterol oxidation in the gastric epithelium may be further sulfated by hydroxysteroid su...

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Detalhes bibliográficos

Principais autores:	Wenting Hong, Fenghua Guo, Mingjie Yang, Dongke Xu, Ziyan Zhuang, Baolin Niu, Qianming Bai, Xiaobo Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-11-01
coleção:	Lipids in Health and Disease
Assuntos:	Gastric epithelial cell Hydroxysteroid Sulfotransferase 2B1 (SULT2B1) Gastric carcinogenesis Oxysterol PI3K/AKT signaling
Acesso em linha:	http://link.springer.com/article/10.1186/s12944-019-1149-6
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