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Functional and mechanistic studies reveal MAGEA3 as a pro-survival factor in pancreatic cancer cells

Abstract Background In the era of personalized therapy, functional annotation of less frequent genetic aberrations will be instrumental in adapting effective therapeutic in clinic. Overexpression of Melanoma associated antigen A3 (MAGEA3) is reported in certain pancreatic cancer (PCA) patients. The...

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Principais autores: Biswajit Das, Shantibhusan Senapati
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-07-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
MAGEA3
Pancreatic cancer
CCL2
Survivin
Autophagy
Cancer testis antigen
Online adgang:http://link.springer.com/article/10.1186/s13046-019-1272-2
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