Skin advanced glycation end-products do not predict pulmonary function trajectories in adults from the ILERVAS cohort

Abstract Advanced glycation end-products (AGEs) activate specific receptors (RAGE) promoting inflammation and oxidative stress. The lungs, with high RAGE expression, may be particularly susceptible to AGE-related injury. This study assessed whether baseline skin AGE levels, measured by skin autofluo...

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Detalhes bibliográficos

Principais autores:	Gerard Torres, Esther Gracia-Lavedan, Jessica González, Mario Henríquez-Beltrán, Adriano D. S. Targa, Maria Royo, Marcelino Bermúdez-López, Eva Castro-Boqué, José Manuel Valdivielso, Reinald Pamplona, Dídac Mauricio, Albert Lecube, Ferran Barbé, Jordi de Batlle, The ILERVAS team
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-01-01
coleção:	Scientific Reports
Assuntos:	Advanced glycation end-products (AGEs) Skin autofluorescence (SAF) Lung function decline Cardiovascular risk
Acesso em linha:	https://doi.org/10.1038/s41598-025-33414-8
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