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Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase.

BACKGROUND:Reactions of vaccinia topoisomerase and the tyrosine site-specific recombinase Flp with methylphosphonate (MeP) substituted DNA substrates, have provided important insights into the electrostatic features of the strand cleavage and strand joining steps catalyzed by them. A conserved argin...

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Detalhes bibliográficos
Principais autores: Chien-Hui Ma, Aashiq H Kachroo, Anna Macieszak, Tzu-Yang Chen, Piotr Guga, Makkuni Jayaram
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2009-09-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2747268?pdf=render
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