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HEXIM1 induces differentiation of human pluripotent stem cells.

Hexamethylene bisacetamide inducible protein 1 (HEXIM1) is best known as the inhibitor of positive transcription elongation factor b (P-TEFb), which is composed of cyclin-dependent kinase 9 (CDK9)/cyclin T1. P-TEFb is an essential regulator for the transcriptional elongation by RNA polymerase II. A...

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Principais autores: Vanessa Ding, Qiao Jing Lew, Kai Ling Chu, Subaashini Natarajan, Vikneswari Rajasegaran, Meera Gurumurthy, Andre B H Choo, Sheng-Hao Chao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2013-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3748041?pdf=render
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