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Antisense Oligonucleotides: Technological Advances, Clinical Progress, and Expanding Therapeutic Frontiers

Antisense oligonucleotides (ASOs) are emerging therapeutic agents that modulate gene expression at the RNA level, offering distinct therapeutic advantages over conventional small-molecule drugs and biologics. By directly targeting RNA, ASOs expand the spectrum of druggable targets to include those p...

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Principais autores: Liping Xu, Huaqun Zhang, Bingchen Jiang, Yuanying Jiang, Hui Lu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-04-01
Serier:Pharmaceutics
Fag:
antisense oligonucleotides
RNA-targeted therapeutics
chemical modification
precision medicine
Online adgang:https://www.mdpi.com/1999-4923/18/4/446
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