Reduced ABCB1 Expression and Activity in the Presence of Acrylic Copolymers
Purpose: P-glycoprotein (P-gp; ABCB1), an integral membrane protein in the apical surface of human intestinal epithelial cells, plays a crucial role in the intestinal transport and efflux leading to changes in the bioavailability of oral pharmaceutical compounds. This study was set to examine the po...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Tabriz University of Medical Sciences
2014-05-01
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| coleção: | Advanced Pharmaceutical Bulletin |
| Assuntos: | |
| Acesso em linha: | http://journals.tbzmed.ac.ir/APB/Abstract/APB_105_20131221162355 |
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