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Th1 Cytokine-Secreting Recombinant Mycobacterium bovis Bacillus Calmette-Guérin and Prospective Use in Immunotherapy of Bladder Cancer

Intravesical instillation of Mycobacterium bovis bacillus Calmette-Guérin (BCG) has been used for treating bladder cancer for 3 decades. However, BCG therapy is ineffective in approximately 30–40% of cases. Since evidence supports the T helper type 1 (Th1) response to be essential in BCG-induced tum...

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Bibliografiske detaljer
Principais autores: Yi Luo, Jonathan Henning, Michael A. O'Donnell
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2011-01-01
Serier:Clinical and Developmental Immunology
Online adgang:http://dx.doi.org/10.1155/2011/728930
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