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Effect of catechol-O-methyltransferase (rs4680) single-nucleotide polymorphism on opioid-induced hyperalgesia in adults with chronic pain

The catechol-O-methyltransferase Val158Met polymorphism has been associated with alterations in pain perception, but the influence of the polymorphism on pain perception in patients with chronic pain receiving daily opioid therapy has not been previously reported. The primary aim of this study was t...

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Bibliographic Details
Main Authors: W Michael Hooten, Danqing Hu, Julie M Cunningham, John L Black
Format: Artigo
Language:Inglês
Published: SAGE Publishing 2019-05-01
Series:Molecular Pain
Online Access:https://doi.org/10.1177/1744806919848929
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