Recurrent fever and association with severe organ involvement, mortality and treatment outcomes in VEXAS syndrome: data from the AIDA Network

IntroductionRecurrent febrile episodes account for one of the most frequent symptoms observed in Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome and a key target for therapeutic intervention. Therefore, this study aims at investigating the association between recurrent febr...

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Glavni autori:	Valeria Caggiano, Jessica Sbalchiero, Micol Frassi, Francesca Crisafulli, Ilaria Cavazzana, Andrea Hinojosa-Azaola, Eduardo Martín-Nares, Guillermo Arturo Guaracha-Basañez, Jiram Torres-Ruiz, Ewa Wiesik-Szewczyk, Anna Nowakowska-Plaza, Paolo Sfriso, Sara Bindoli, Samuele Rizzo, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Olga Araújo, Henrique A. Mayrink Giardini, Andrés González-García, Giuseppe Lopalco, Ombretta Viapiana, Riccardo Bixio, Abdurrahman Tufan, Pravin Hissaria, Mark Beecher, Alicia Callisto, Amato De Paulis, Lorenzo Dagna, Corrado Campochiaro, Alessandro Tomelleri, Serena Bugatti, Alessandra Milanesi, Guillermo Ruiz-Irastorza, Adriana Soto-Peleteiro, Matteo Piga, Alberto Cauli, Fabrizio Conti, Chiara Cardamone, Paola Triggianese, Carmelo Gurnari, Rosetta Vitetta, Marcella Prete, Vito Racanelli, Rosaria Talarico, Francesco Ferro, Federica di Cianni, Maria Chiara Cuccaro, Adrián Mayo-Juanatey, Alessandra Renieri, Vincenzo Sorrentino, Mehmet Ali Ergun, Alberto Balistreri, Bruno Frediani, Monica Bocchia, Claudia Fabiani, Luca Cantarini, Antonio Vitale
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2026-03-01
Serija:	Frontiers in Immunology
Teme:	anakinra autoinflammatory disease JAK personalized medicine prognosis tocilizumab (TCZ)
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1753412/full
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