Cerebrospinal Pharmacokinetic Modeling and Pharmacodynamic Simulation of High-Dose Cefazolin for Meningitis Caused by Methicillin-Susceptible <i>Staphylococcus aureus</i>

<b>Background:</b> Cefazolin is being increasingly used to treat central nervous system infections caused by methicillin-susceptible <i>Staphylococcus aureus</i> (MSSA) to mitigate the side effects of existing anti-Staphylococcal drugs. This study aims to develop a cerebrospi...

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Bibliografiske detaljer
Main Authors: Tetsushu Onita, Kazuro Ikawa, Noriyuki Ishihara, Hiroki Tamaki, Takahisa Yano
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-10-01
Serier:Antibiotics
Fag:
cefazolin
meningitis
staphylococcal
renal
Online adgang:https://www.mdpi.com/2079-6382/14/10/1008
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