Calpains of Leishmania braziliensis: genome analysis, differential expression, and functional analysis

BACKGROUND Calpains are proteins belonging to the multi-gene family of calcium-dependent cysteine peptidases that undergo tight on/off regulation, and uncontrolled proteolysis of calpains is associated with severe human pathologies. Calpain orthologues are expanded and diversified in the trypanosom...

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Autores principales:	Vítor Ennes-Vidal, Bianca da Silva Vitório, Rubem Figueiredo Sadok Menna-Barreto, André Nóbrega Pitaluga, Silvia Amaral Gonçalves-da-Silva, Marta Helena Branquinha, André Luis Souza Santos, Claudia Masini d’Avila-Levy
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Fundação Oswaldo Cruz (FIOCRUZ)
Colección:	Memorias do Instituto Oswaldo Cruz
Materias:	cysteine peptidases calcium-dependent peptidase leishmaniasis trypanosomatid
Acceso en línea:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100347&lng=en&tlng=en
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