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AKAP12 Signaling Complex: Impacts of Compartmentalizing cAMP‐Dependent Signaling Pathways in the Heart and Various Signaling Systems

Abstract Heart failure is a complex clinical syndrome, represented as an impairment in ventricular filling and myocardial blood ejection. As such, heart failure is one of the leading causes of death in the United States. With a mortality rate of 1 per 8 individuals and a prevalence of 6.2 million Am...

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Principais autores: Hanan Qasim, Bradley K. McConnell
פורמט: Artigo
שפה:Inglês
יצא לאור: Wiley 2020-07-01
סדרה:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
נושאים:
adrenergic receptor
AKAP12
compartmentalization
gravin
PKA
signaling pathways
גישה מקוונת:https://www.ahajournals.org/doi/10.1161/JAHA.120.016615
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