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Use of Toll-Like Receptor Agonists to Induce Ectopic Lymphoid Structures in Myasthenia Gravis Mouse Models

Myasthenia gravis (MG) is an autoimmune disease mediated by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction. MG symptoms are characterized by muscle weaknesses. The thymus of MG patients is very often abnormal and possesses all the characteristics of tertiary l...

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Principais autores: Marieke Robinet, Bérengère Villeret, Solène Maillard, Mélanie A. Cron, Sonia Berrih-Aknin, Rozen Le Panse
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-08-01
Serier:Frontiers in Immunology
Fag:
toll-like receptor
lipopolysaccharide
poly(I:C)
autoimmunity
B cells
myasthenia gravis
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01029/full
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