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The interplay between autophagy and cGAS-STING signaling and its implications for cancer

Autophagy is an intracellular process that targets various cargos for degradation, including members of the cGAS-STING signaling cascade. cGAS-STING senses cytosolic double-stranded DNA and triggers an innate immune response through type I interferons. Emerging evidence suggests that autophagy plays...

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Principais autores: Maximilian Schmid, Patrick Fischer, Magdalena Engl, Joachim Widder, Sylvia Kerschbaum-Gruber, Dea Slade
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-04-01
coleção:Frontiers in Immunology
Assuntos:
autophagy
cGAS/STING signaling
innate immunity
cancer
radiotherapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1356369/full
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