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Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice

Hypertension may develop before or after the onset of diabetes and it is known to increase the risk of developing diabetic nephropathy. Alpha-1 antitrypsin (AAT) is a multi-functional protein with beneficial effects in various diseases but its role in reducing blood pressure in the diabetic kidney h...

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Hlavní autoři: Carlos I. Lugo, Lauren P. Liu, Niharika Bala, Angelica G. Morales, Mohammed F. Gholam, Julia C. Abchee, Nasseem Elmoujahid, Ahmed Samir Elshikha, Rigena Avdiaj, Louis A. Searcy, Nancy D. Denslow, Sihong Song, Abdel A. Alli
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-12-01
Edice:Biomolecules
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On-line přístup:https://www.mdpi.com/2218-273X/13/1/66
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