Biophysical characterisation of the recombinant human frataxin precursor

Friedreich's ataxia is a disease caused by a decrease in the levels of expression or loss of functionality of the mitochondrial protein frataxin (FXN). The development of an active and stable recombinant variant of FXN is important for protein replacement therapy. Although valuable data about the ma...

詳細記述

書誌詳細

主要な著者:	Ignacio Hugo Castro, Alejandro Ferrari, María Georgina Herrera, Martín Ezequiel Noguera, Lorenzo Maso, Monica Benini, Alessandra Rufini, Roberto Testi, Paola Costantini, Javier Santos
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2018-03-01
シリーズ:	FEBS Open Bio
主題:	aggregation conformation Friedreich's ataxia precursor stability unfolding
オンライン･アクセス:	https://doi.org/10.1002/2211-5463.12376
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!