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Understanding Natural Killer cell regulation by mathematical approaches

The activity of Natural Killer (NK) cells is regulated by various processes including education/licensing, priming, integration of positive and negative signals through an array of activating and inhibitory receptors and the development of memory-like functionality. These processes are often very co...

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Principais autores: Carsten eWatzl, Michal eSternberg-Simon, Doris eUrlaub, Ramit eMehr
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2012-12-01
Serier:Frontiers in Immunology
Fag:
Systems Biology
proliferation
mathematical modeling
inhibitory receptors
Natural Killer cells
Signaling Pathways
Online adgang:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00359/full
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