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Inhibitory effects of luteolin on TLR3-mediated inflammation caused by TAK/NF-κB signaling in human corneal fibroblasts

AIM: To study the role of luteolin (LUT) in the expression of toll-like receptors 3 (TLR3) ligand polyI:C stimulated inflammatory factors in human corneal fibroblasts (HCFs). METHODS: HCFs cells were cultivated with or without LUT or polyI:C. The expression levels of interleukin (IL)-6, IL-8, monocy...

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Main Authors: Zi-Han Guo, Ping-Ping Liu, Heng Wang, Xiu-Xia Yang, Cheng-Cheng Yang, Hui Zheng, Dan Tang, Yang Liu
Format: Artigo
Language:Inglês
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-03-01
Series:International Journal of Ophthalmology
Subjects:
toll-like receptor
inflammation
corneal fibroblast
polyi:c
Online Access:http://ies.ijo.cn/en_publish/2022/3/20220301.pdf
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