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Machine learning-driven prediction of substrates for enzymes introducing or removing protein post-translational modifications

Abstract The exploration of post-translational modifications (PTMs) within the proteome is pivotal for advancing our understanding of disease and the function of cancer therapeutics. However, identifying genuine sites of PTMs introduced or removed by an enzyme of interest amid numerous candidates is...

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Bibliografische gegevens
Hoofdauteurs: Nashira H. Ridgeway, Anand Chopra, Valentina Lukinović, Michal Feldman, François Charih, Dan Levy, James R. Green, Kyle K. Biggar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2025-11-01
Reeks:Communications Chemistry
Online toegang:https://doi.org/10.1038/s42004-025-01717-6
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