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An exploratory study on the application of nanopore sequencing for detecting Mycobacterium tuberculosis drug resistance in respiratory specimens

Abstract Background This study aimed to evaluate the diagnostic efficacy of nanopore sequencing for Mycobacterium tuberculosis (MTB) drug resistance in respiratory specimens from pulmonary tuberculosis (PTB) patients. It compared it to the Xpert MTB/RIF and fluorescent polymerase chain reaction (PCR...

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Principais autores: Niansa Wei, Feiyi Du, Wenjuan Nie, Yingxing Nong, Yanrong Lin, Aichun Huang, Shaoyong Xi, Yiyi Lan, Xiaoyang Luo, Shixiong Yang, Qingdong Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-06-01
coleção:BMC Pulmonary Medicine
Assuntos:
Nanopore sequencing
Mycobacterium tuberculosis
Drug resistance
Respiratory specimens
Acesso em linha:https://doi.org/10.1186/s12890-025-03747-1
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