The Interactions of H₂TMPyP, Analogues and Its Metal Complexes with DNA G-Quadruplexes—An Overview

The evidence that telomerase is overexpressed in almost 90% of human cancers justifies the proposal of this enzyme as a potential target for anticancer drug design. The inhibition of telomerase by quadruplex stabilizing ligands is being considered a useful approach in anticancer drug design proposal...

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Principais autores:	Catarina I. V. Ramos, Ana R. Monteiro, Nuno M. M. Moura, Maria Amparo F. Faustino, Tito Trindade, Maria Graça P. M. S. Neves
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-09-01
Series:	Biomolecules
Assuntos:	aromatic ligands porphyrins metalloporphyrins H<sub>2</sub>TMPyP Ag<sup>II</sup>TMPyP G-quadruplexes
Acceso en liña:	https://www.mdpi.com/2218-273X/11/10/1404
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