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Cell Cycle Changes, DNA Ploidy, and PTTG1 Gene Expression in HTLV-1 Patients

Human T-cell lymphotropic virus type-1 (HTLV-1) is a pathogenic retrovirus that is associated with adult T-cell leukemia/lymphoma (ATL). Genetic instability is the hallmark of ATL. Cell cycle progression is needed for virus particle reproduction. HTLV-1 encoded Tax protein ultimately disrupts the mi...

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Autori principali: Debora Levy, Mari Cleia M. R. Ferreira, Cadiele O. Reichert, Lis Vilela de Almeida, Graciela Brocardo, Luis Alberto P. C. Lage, Hebert F. Culler, Youko Nukui, Sergio P. Bydlowski, Juliana Pereira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020-07-01
Serie:Frontiers in Microbiology
Soggetti:
HTLV-1
ATL
PTTG1
cell cycle
T-cell lymphocytes
Accesso online:https://www.frontiersin.org/article/10.3389/fmicb.2020.01778/full
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