Cholinergic basal forebrain degeneration is associated with central fatigue in Parkinson’s disease

BackgroundCentral fatigue is a prevalent and debilitating non-motor symptom in Parkinson’s disease (PD), yet its neurobiological basis remains poorly understood. While cholinergic basal forebrain (CBFB) degeneration has been implicated in various PD symptoms, its specific relationship with central f...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li Li, Xiaodan Zhang, Mateng Wang, Yuemin Wu, Zhaoying Chen, Yafen Jiang, Timonthy Rainer, Qiongfeng Guan, Weinv Fan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2025-11-01
Cyfres:Frontiers in Neurology
Pynciau:
Parkinson disease
central fatigue
cholinergic system
basal forebrain
grey matter density
grey matter volume
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fneur.2025.1682573/full
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