Cholesterol promotes IFNG mRNA expression in CD4 + effector/memory cells by SGK1 activation
The study shows that cholesterol modulates IFNG expression in CD4 + T cells via SGK1 activation, suggesting lipid pathways as potential targets for regulating immune responses in the CNS. IFNγ-secreting T cells are central for the maintenance of immune surveillance within the central nervous system...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2024-12-01
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| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402890 |
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