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Novel haplotypes of genetic polymorphisms in alcohol metabolizing enzymes in Kampala, Uganda

Abstract Objective Alcohol is metabolized to acetaldehyde by alcohol dehydrogenases (ADH) and subsequently to acetate by aldehyde dehydrogenases (ALDH). Single nucleotide polymorphisms (SNPs) in ADH1B, ADH1C and ALDH2 genes lead to haplotypes encoding isozymes which influence development of alcoholi...

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Bibliografiske detaljer
Principais autores: Rodney Okwasiimire, Rhona K. Baingana, Dennis M. Kasozi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-07-01
Serier:BMC Research Notes
Fag:
Online adgang:https://doi.org/10.1186/s13104-025-07331-y
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