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Foot-and-Mouth Disease Virus Evades Innate Immune Response by 3C-Targeting of MDA5

Foot-and-mouth disease (FMD) is a highly contagious disease caused by FMD virus (FMDV) in cloven-hoofed animals. Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated gene 5 (MDA5) are representative receptors in the cytoplasm for the detection of viral RNA and trigger antiv...

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Principais autores: Hyejin Kim, Ah-Young Kim, Jieun Choi, Sun Young Park, Sang Hyun Park, Jae-Seok Kim, Sim-In Lee, Jong-Hyeon Park, Choi-Kyu Park, Young-Joon Ko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-01-01
coleção:Cells
Assuntos:
foot-and-mouth disease virus
MDA5
non-structural protein
3C
innate immune response
Acesso em linha:https://www.mdpi.com/2073-4409/10/2/271
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