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Single-cell mass spectrometry imaging of lipids in HeLa cells via tapping-mode scanning probe electrospray ionization

Abstract The development of analytical technology that allows investigation of the diversity of cells that form biological tissues based on molecular information is important to elucidate the heterogeneity of cells and pathological mechanisms. Here, we present a proof-of-concept demonstration of sin...

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Bibliografiske detaljer
Main Authors: Yoichi Otsuka, Kazuya Kabayama, Ayane Miura, Masatomo Takahashi, Kosuke Hata, Yoshihiro Izumi, Takeshi Bamba, Koichi Fukase, Michisato Toyoda
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-05-01
Serier:Communications Chemistry
Online adgang:https://doi.org/10.1038/s42004-025-01521-2
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