Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study

Abstract Amyotrophic lateral sclerosis (ALS) patients lack effective treatments to maintain motor and neuromuscular function. This study aimed to evaluate the effect of a home-based exercise program on muscle strength, ALS scores, and transcriptome in ALS patients, Clinical Trials.gov #NCT03201991 (...

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Hlavní autoři:	Omar Jawdat, Jason Rucker, Tomoki Nakano, Kotaro Takeno, Jeffery Statland, Mamatha Pasnoor, Mazen M. Dimachkie, Carla Sabus, Yomna Badawi, Suzanne L. Hunt, Naoko H. Tomioka, Sumedha Gunewardena, Clark Bloomer, Heather M. Wilkins, Laura Herbelin, Richard J. Barohn, Hiroshi Nishimune
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-09-01
Edice:	Scientific Reports
Témata:	Amyotrophic lateral sclerosis Clinical trial Exercise
On-line přístup:	https://doi.org/10.1038/s41598-024-72355-6
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