Single Molecule Study of the Polymerization of RecA on dsDNA: The Dynamics of Individual Domains

In the Escherichia coli, RecA plays a central role in the recombination and repair of the DNA. For homologous recombination, RecA binds to ssDNA forming a nucleoprotein filament. The RecA-ssDNA filament searches for a homologous sequence on a dsDNA and, subsequently, RecA mediates strand exchange be...

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Principais autores:	Nitzan Maman, Pramod Kumar, Amarjeet Yadav, Mario Feingold
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-03-01
coleção:	Frontiers in Molecular Biosciences
Assuntos:	single molecule recA optical tweezers protein-DNA interaction nucleation and growth
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmolb.2021.609076/full
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