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Targeting fructose metabolism by glucose transporter 5 regulation in human cholangiocarcinoma

Alterations in cellular metabolism may contribute to tumor proliferation and survival. Upregulation of the facilitative glucose transporter (GLUT) plays a key role in promoting cancer. GLUT5 mediates modulation of fructose utilization, and its overexpression has been associated with poor prognosis i...

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Principais autores: Nattawan Suwannakul, Napat Armartmuntree, Raynoo Thanan, Kaoru Midorikawa, Tetsuo Kon, Shinji Oikawa, Hatasu Kobayashi, Ning Ma, Shosuke Kawanishi, Mariko Murata
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2022-11-01
coleção:Genes and Diseases
Assuntos:
Cholangiocarcinoma
Fructose
Glucose transporter 5
Metabolic regulation
Warburg effect
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352304221001100
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