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Noradrenaline release from the locus coeruleus shapes stress-induced hippocampal gene expression

Exposure to an acute stressor triggers a complex cascade of neurochemical events in the brain. However, deciphering their individual impact on stress-induced molecular changes remains a major challenge. Here, we combine RNA sequencing with selective pharmacological, chemogenetic, and optogenetic man...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Mattia Privitera, Lukas M von Ziegler, Amalia Floriou-Servou, Sian N Duss, Runzhong Zhang, Rebecca Waag, Sebastian Leimbacher, Oliver Sturman, Fabienne K Roessler, Annelies Heylen, Yannick Vermeiren, Debby Van Dam, Peter P De Deyn, Pierre-Luc Germain, Johannes Bohacek
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2024-03-01
Schriftenreihe:eLife
Schlagworte:
transcriptome
noradrenaline
locus coeruleus
hippocampus
stress
optogenetics
Online-Zugang:https://elifesciences.org/articles/88559
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