Mitochondrial Dysfunction Is Inducible in Lymphoblastoid Cell Lines From Children With Autism and May Involve the TORC1 Pathway

We previously developed a lymphoblastoid cell line (LCL) model of mitochondrial dysfunction in autism spectrum disorder (ASD); some individuals with ASD showed mitochondrial dysfunction (AD-A) while other individuals (AD-N) demonstrated mitochondrial respiration similar to controls (CNT). To test th...

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Principais autores:	Sirish C. Bennuri, Shannon Rose, Richard E. Frye
格式:	Artigo
语言:	Inglês
出版:	Frontiers Media S.A. 2019-05-01
丛编:	Frontiers in Psychiatry
主题:	autism mitochondria mitoplasticity mechanistic target of rapamycin reactive oxygen species
在线阅读:	https://www.frontiersin.org/article/10.3389/fpsyt.2019.00269/full
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