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Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

With the growing body of knowledge on the contribution of efflux activity to Mycobacterium tuberculosis drug resistance, increased attention has been given to the use of efflux inhibitors as adjuvants of tuberculosis therapy. Here, we investigated how efflux activity modulates the levels of efflux b...

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Principais autores: Diana Machado, João Perdigão, Isabel Portugal, Marco Pieroni, Pedro A. Silva, Isabel Couto, Miguel Viveiros
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-03-01
coleção:Antibiotics
Assuntos:
efflux inhibitors
lineages
mutations
resistance levels
tuberculosis
verapamil
Acesso em linha:http://www.mdpi.com/2079-6382/7/1/18
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